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What is GeneScreen?

USC GeneScreen, USC Alzheimer's Prevention Registry, is a registry for Los Angeles community members who want to partner with researchers leading the fight against Alzheimer's disease. Registry members are the first to hear about new and innovative studies that they may be eligible to participate in.
Am I eligible to join the registry? If you meet the following 3 criteria, the answer is YES.

No diagnosis of dementia

Age 40 years or older

Live in the Los Angeles area

The registry is an important partnership between researchers at the University of Southern California and the community we serve.  It is maintained by the Alzheimer's Disease Research Center at USC (USC ADRC), funded by the National Institutes of Health to improve care for people with memory loss, Alzheimer disease, and dementia through research.

Researchers at USC invite you, and your friends and family, to enroll online in USC GeneScreen, USC Alzheimer's Prevention Registry.

As a registry member, you will be among the first contacted by USC researchers to participate in studies for which you may be eligible. It is your decision to accept or decline matched studies.

There is no cost to join the registry. Enrollment takes minutes and includes a brief online survey and consent. A home cheek swab sample kit is used to learn your ApoE genotype. The ApoE gene increases risk for Alzheimer's. Your result will be included in the registry, but not shared with you.

You will be compensated for your time with a $25 gift card. Clinical study matches may also offer additional compensation for your participation.

Reduced brain function (cognitive decline), including memory issues, affects 1 in 9 adults in the U.S. Alzheimer's disease is a type of dementia that affects memory, thinking, and behavior. It is a progressive brain disorder that gradually affects cognitive abilities, making it increasingly difficult for people to carry out daily activities. Alzheimer's disease impacts us all.

Researchers need people like you to partner with us in the fight against Alzheimer's disease. Community participation in clinical studies drives important scientific progress that helps us better understand Alzheimer's, ultimately improving prevention and treatment options for everyone.


Why Do We Need
Your Help?

Funded by the NIH, the USC ADRC focuses on mild cognitive changes related to aging, Alzheimer’s disease and cerebrovascular disease (CVD) in multi-ethnic communities. The USC ADRC has three overarching goals:

  • To elucidate vascular contributions to Alzheimer’s disease;

  • To catalyze local research in Alzheimer’s disease at USC (especially Phase I/Phase II clinical trials); and

  • To contribute expertise in vascular disease and imaging to national collaborative initiatives.

USC Alzheimer's Disease Research Center

Dedication. Expertise. Passion.


    Alzheimer's Studies at USC ADRC     


Healthier Vessels
Healthier Brain Study

Understanding how diabetes, hypertension, and high cholesterol affect blood vessels, brain health and memory.

Learn more: English Spanish


Sex Differences in Vascular Contributions to Dementia and Genetic Risk Factors for Alzheimer’s Disease Study (SDVCD)

Learning how genetic risk factors and changes in the brain’s vascular system may be related to an increased risk for developing Alzheimer’s disease.


Dynamic Vasomotor

Reactivity Study (DVR)

Examining the response in blood

vessels to changes in blood flow,

carbon dioxide, and oxygen.

Learn more: English

Image by Towfiqu barbhuiya

Studying the link between

diabetes and brain health in the

Latino/a population.

Learn more: English Spanish

Exciting research projects are happening at USC ADRC all the time. New and innovative studies are always underway or getting started. We need your help to drive this important Alzheimer's research forward. Here are just a few of USC ADRC research studies right now.

USC GeneScreen Team

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